Derivative of -4sin(4x+180)

1. The derivative of a constant times a function is the constant times the derivative of the function.

   1. Let $u = 4 x + 180$.

   2. The derivative of sine is cosine:

      $$\frac{d}{d u} \sin{\left(u \right)} = \cos{\left(u \right)}$$

   3. Then, apply the chain rule. Multiply by $\frac{d}{d x} \left(4 x + 180\right)$:

      1. Differentiate $4 x + 180$ term by term:

         1. The derivative of a constant times a function is the constant times the derivative of the function.

            1. Apply the power rule: $x$ goes to $1$

            So, the result is: $4$

         2. The derivative of the constant $180$ is zero.

         The result is: $4$

      The result of the chain rule is:

      $$4 \cos{\left(4 x + 180 \right)}$$

   So, the result is: $- 16 \cos{\left(4 x + 180 \right)}$

2. Now simplify:

   $$- 16 \cos{\left(4 x + 180 \right)}$$

The answer is:

$$- 16 \cos{\left(4 x + 180 \right)}$$